Helen Pensanti, M.D.

Quick Order Natural Hormones Dr. Pensanti Interview with John R. Lee M.D.

Dr. Helen Pensanti Discussion

Hello Everybody!!! Here is some interesting info I got from Dr John R. Lee's research assistant and author in her own right Virginia Hopkins who writes:
  1. "The earliest clinical study that we know of on progesterone and breast cancer was done at Johns Hopkins University back in 1981 (Cowan et al, American Journal of Epidemiology). They measured estrogen and progesterone in a group of women, then divided them into two groups: those with normal progesterone levels and those with low progesterone levels. They followed these women for 20 years and found that in the women with low progesterone, the incidence of breast cancer was over 80 percent greater than those with normal progesterone, and the incidence of all cancers was ten times higher than in women with normal progesterone.
  2. In 1996, researchers measured women’s progesterone before breast cancer surgery and found that those with normal progesterone levels had an 18-year survival rate—twice that of women with low progesterone at the time of surgery. (Mohr et al, British Journal of Cancer)
  3. Three studies in particular have shown progesterone’s effect on breast cells. One, by Foidart et al and published in the journal Fertility and Sterility in 1998 concluded, “Exposure to progesterone for 14 days reduced the estradiol-induced proliferation of normal breast epithelial cells in vivo.” Another, by Malet et al and published in the Journal of Steroid Biochemistry and Molecular Biology, in 2000 concluded, “Cells exhibited a proliferative appearance after E2 [estradiol] treatment, and returned to a quiescent appearance when Progesterone was added to E2. Progesterone appear(s) predominantly to inhibit cell growth, both in the presence and absence of E2.”

    The third study tested the effects of transdermal (rubbed into the skin) hormones in healthy young women planning to undergo minor breast surgery for aesthetic reasons or for benign breast disease. Ten to 13 days before surgery, four groups of women applied either estradiol cream, progesterone cream, a combination of estradiol and progesterone or a placebo cream (with no hormones in it). At surgery, biopsies were done to measure estrogen and progesterone levels, and the level of cell proliferation rates. (High levels of cell proliferation is a marker for breast cancer.) The study demonstrated that both hormones were well absorbed through the skin into the breast tissue. But even more significant, estradiol increased cell proliferation by 230 percent, whereas progesterone decreased it by more than 400 percent. The estradiol-progesterone combination maintained the normal proliferation rate. (Chang et al, Fertility and Sterility)

  4. In 2002, a French study of HRT in 3,175 women was released. This was particularly interesting because it was a large study, and because, to quote the study, “...the main specificity of the French cohort is that 83% of the combined HRT users were receiving mostly or exclusively a transdermal estradiol gel formulation, and the progestin was oral micronized progesterone in 58%, while MPA users were less than 3%.” Oral micronized progesterone is bioidentical, natural progesterone, which is what most French women use, rather than the synthetic progestins. The conclusion of the study was that, “When both duration of use and the last period of use were analyzed together, no significant increase in breast cancer incidence was observed in any of the four subgroups considered,” and “From internal analysis, there was no significant increase in the risk of breast cancer related to use of the specific type of HRT most prescribed in France.”

Moderation and Common Sense are the Keys to Optimal Health

One of the aspects of Dr. Lee’s character that I admired most was his willingness to change course and moderate his message when new evidence was brought to his attention. He was first led to progesterone when he realized that the conventional HRT he had been prescribing for years had probably harmed many women. He had the courage to admit this first to himself, then to his patients, and he then set about solving the puzzle of how to help women balance their hormones safely and effectively. The discovery of progesterone as a neglected piece of the hormone balance puzzle was exciting and yes, he was a man on a mission to help women balance their hormones and to help undo the damage of conventional HRT. As a result of his courage and zeal, millions of women are healthier and happier.

From the beginning, Dr. Lee recommended no more than 15 to 30 mg of progesterone daily doses of progesterone in any form over a long period of time. That’s just not good medicine, it’s not balanced, it’s not common sense, and it’s bound to cause trouble sooner or later. In his first self-published book for doctors, Dr. Lee likened the “dance of the steroids” to an orchestra, where each player creates beautiful music by being in harmony and rhythm with the others. Large doses of progesterone will drown out the other players and create chaos.

As zealous as Dr. Lee was about progesterone, his message was never just about one hormone. He always strongly advocated a wholesome diet, moderate exercise, good sleep, stress management, healthy relationships with others, and the importance of making time for fun and for contemplation. "



Helen Pensanti M.D.

Research Info Archives

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  3. 7 Edible Weeds
  4. 7 Steps to Healing
  5. 10 Foods You Should NEVER EAT!!
  6. 10 Things You Must Do To Beat Breast Cancer Now
  7. 10 Ways to Increase Energy
  8. Acne
  9. Age Spots
  10. Alzheimer's Prevention Plan
  11. Aloe Vera Freeze Dried Capsules and AloeVera Liquid Concentrate
  12. Anti-Aging Tips
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  14. Arteries Clean
  15. Arthritis
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  17. Baby Boomers and Alzheimer’s Disease
  18. Bacteria and Viral Infections
  19. Bananas are healthy!
  20. Beating Breast Cancer with Nutrition
  21. Belly Fat
  22. Beta Glucan
  23. Beauty of Mathematics
  24. Bio-Identical VS Synthetic Hormones
  25. Bladder Infection Help - Parsley Tea
  26. Blood Clots
  27. Breast Cancer Inducing Chemicals
  28. Breast Cancer Profile
  29. Breast Cancer and Synthetic Hormones
  30. Buying and Preparing Fresh Fish
  31. Cancer Prevention Tips - Stay Cancer Proof
  32. Cancer Protection List - Household Items to Avoid
  33. Cataracts
  34. Chelation Therapy
  35. Clustered Water/Healthy Immune System
  36. Cold Sores
  37. Constipation
  38. Cortisol and Weight Loss
  39. Calories and Calore Counting
  40. Cystitis
  41. Dark Spots On Bananas - Anti Cancer
  42. Date Rape Drug Information - GHB
  43. Dental Problems
  44. Diabetes
  45. Diabetes Mellitus
  46. Diabetes Travel Tips
  47. Diseases Do Not Just Happen
  48. Dr Helen's 1200 Calorie Diet to lose 45 pounds in 3 months
  49. Eating Genetically Modified Fruits
  50. Eliminate "White Poison" From Your Diet
  51. Estrogen Found in Foods/Herbs/Drugs/Chemicals
  52. Estrogen Inhibiting Foods
  53. Fatigue
  54. Fatigue and Loss of Energy
  55. Five Keys to Restoration
  56. Food Toxins
  57. Foot Health
  58. General Question About Natural Hormones
  59. Hair growth in unwanted places
  60. Hair Loss
  61. Headache Check Lists - Headache Symptoms and Headache Causes
  62. Healing properties of garlic and onions
  63. Healing / Water Clusters
  64. Health Updates
  65. Healthly Foods Chart for Bone Health
  66. Healthly Foods Chart
  67. Healthy Food List
  68. Healthy Living Recipe Options
  69. Heart Disease - #1 Cause of Death In America
  70. Heart Disease and Women - Estrogen does not benefit the heart.
  71. High Blood Pressure - Hypertension
  72. Hepatitis
  73. Highlights from Dr Abraham's interview at the 6th Annual Anti-Aging Conference
  74. Holiday Meals
  75. Hormone Replacement Therapy (HRT) linked to Hearing Loss
  76. Hormone Studies
  77. Inflammation Reduction
  78. Insomnia Information
  79. Keeping Your Liver Healthy
  80. Laser Vision Correction
  81. LeAine Dehmer Clinical Skincare Specialist Answers Your Questions
  82. Long Life and Aging
  83. Lose 45 Pounds In 3 Months
  84. Mamograms - Infrared Thermography
  85. Managing Lactose Intolerance
  86. Mascular Degeneration
  87. Men and Progesterone
  88. Men's Prostate Health
  89. Microbes in an overweight body are more efficient at extracting calories from food.
  90. Mind Boosters
  91. Natural Cancer Treatments
  92. Natural Progesterone and Blood Pressure/Inflammmation
  93. Non Toxic Hair Dyes
  94. Olive Leaf Extract
  95. Organic Dark Unprocessed Chocolate
  96. Osteoarthritis and Musculoskeletal Health
  97. Osteoporosis Prevention
  98. Osteoporosis - Softening of the Bones
  99. Overcoming Anxiety and Depression without Drugs!
  100. Parasitic Infections
  101. Parkinson's Desease
  102. Prostate Cancer & PC Spes
  103. Purify your Home without Poisons Chemicals
  104. Red Clover; Health Benefits of Isoflavones
  105. Phosphatidylserine (PS)
  106. Potassium In The News
  107. Preserving Your Sight
  108. Progesterone - Calming Effects
  109. Progesterone and Breast Cancer Study
  110. Progesterone, can we use that name?
  111. Progesterone, does it build up in your fat cells?
  112. Progestin VS Natural Progesterone
  113. Phyto-Progesterone is now called Diosgenin
  114. Recommended Supplements for Anti-Aging
  115. Seasonal Affective Disorder
  116. Seasonal Allergies
  117. Secret Remedies
  118. Shaping Children's Eating Habits
  119. Signs of Estrogen Deficiency
  120. Signs of Estrogen Excess
  121. Signs of Progesterone Excess
  122. Sinus Problems
  123. Six Types of Mothers
  124. Soy Foods May Protect the Body from Cancer
  125. Symptoms of Low Thyroid
  126. Synthetic Hormones and Breast Cancer
  127. Testosterone - how women can increase or decrease Testosterone Levels
  128. Thinning Hair
  129. Tinnitus
  130. Tips for Traveler's Health
  131. Top Ten Reasons to Get Off Synthetic Hormones
  132. Toxic Shampoos
  133. Type II Diabetes - Insulin Resistance
  134. Vaginal Dryness - High In Oxalate Foods to Avoid
  135. Vitamin A
  136. Vitamin B
  137. Vitamin Bible and Healthy Tips
  138. Vitamin D - emphasizing the importance of supplementing with Vitamin D
  139. Vitamin E - may provide women with protection from breast cancer
  140. Vitamin K
  141. Ways to fit fiber in your diet
  142. Weight Loss
  143. Wellness Plan
  144. West Nile Virus
  145. What to look for in a Biological Dentist
  146. Why Natural Progesterone is better than Synthetic
  147. Women and Heart Disease
  148. Word... Water... Walk...
  149. Wyeth Pharmaceutical lies in study

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